Abstract

In the present study, the aim was to explore the quality of life of thalassaemia major (TM) patients according to age, sex, school performance, severity and complications of the disease. A cross-sectional descriptive study was conducted. Quality of life was evaluated by 4 questionnaires; demographic characteristics, the short form 36 health survey (SF-36), Persian version of symptoms checklist-90-revised (SCL-90-R) and life satisfaction index (LSI). 687 (41.08) of the eligible patients with TM completed the questionnaires. With the SF-36 questionnaire, 329 (47.9) participants had an excellent level of physical functioning. With the SCL-90-R questionnaire, 446 (64.9) participants had a global severity index of > 0.7, considered psychiatric patients, 141 (20.5) patients had GSI between 0.4 and 0.7, considered suspected psychiatric patients and 100 (14.6) participants had GSI of < 0.4, considered non-psychiatric patients. The mean score of LSI questionnaire was 20.50 (SD 5.95), range 2-37. Beta- TM patients are at risk of psychiatric symptoms and need appropriate psychiatric counselling.