(2011) Production of hen egg yolk antibody against zoonotic disease (salmonellosis) and passive immunization in mice. Advances in Environmental Biology. pp. 3710-3715. ISSN 19950756 (ISSN)
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Production of hen egg yolk antibody against zoonotic disease (salmonellosis) and passive immunization in mice.pdf Download (193kB) |
Abstract
Salmonellosis as joint human and animal diseases is very important, in this sudy; White egg-laying hens were immunized with Salmonella (S.) typhi and S. typhimurium-heat-killed whole cells in Freund's adjuvant. Immunization was done with 107 c.f.u of bacteria injection into the breast muscle of each egg-laying hen. Specific antibodies were detected by the enzyme-linked immunosorbent assay in the serum and in eggs. The effect of oral passive immunization was evaluated with egg yolk antibodies against Salmonella typhimurium in controlled experimental salmonellosis in mice. Chicken egg yolk antibodies (IgY) were raised against S. typhimuruim in the serum and in eggs as well. Anti-S. typhimurium IgY cross-reacted by 63, 25 and 14 with S. typhi, Shigella dysenteriae and E. coli respectively.Results suggest that egg yolk antibodies specific for salmonella protect mice from experimental salmonellosis. Hence, eggs from hens immunized with S. typhi or S. typhimuruim have the potential as a useful source for passive immunity.
| Item Type: | Article |
|---|---|
| Keywords: | ELISA Immunoglobulin Y (IgY) Salmonellosis Zoonotic disease Animalia Bacteria (microorganisms) Escherichia coli Mus Salmonella Salmonella typhi Salmonella typhimurium Shigella dysenteriae |
| Divisions: | |
| Page Range: | pp. 3710-3715 |
| Journal or Publication Title: | Advances in Environmental Biology |
| Journal Index: | Scopus |
| Volume: | 5 |
| Number: | 12 |
| ISSN: | 19950756 (ISSN) |
| Depositing User: | مهندس مهدی شریفی |
| URI: | http://eprints.bmsu.ac.ir/id/eprint/1244 |
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