Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Survival rate and complications of palliative bypass surgery in advanced cancer of the ampulla of vater and pancreatic head

(2017) Survival rate and complications of palliative bypass surgery in advanced cancer of the ampulla of vater and pancreatic head. Iranian Journal of Epidemiology. pp. 68-74. ISSN 17357489 (ISSN)

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Abstract

Background and Objectives: The cancer of the pancreatic head and Ampulla of Vater is a malignant disease usually seen in advanced stages with symptoms caused by stomach and biliary obstruction. Curative treatment is possible in the early stage. Unfortunately, most symptomatic patients are in the advanced stage and have an unrespectable tumor; therefore, they should undergo palliative surgery. This study was performed to determine the complications and survival rate of patients who underwent palliative surgery for advanced stages of cancer in the Ampulla Vater and pancreatic head. Methods: In this study, 49 patients with advanced stages of cancer in the Ampulla of Vater and pancreatic head who had undergone palliative surgery from 2003 to 2014 at Baqiyatallah Hospital were studied and the complications and survival rate were determined. Results: Eleven patients (22.44) underwent biliary bypass, 6 (12.24) underwent gastric bypass, and 32 (65.32) underwent both procedures. Twelve (24.49) patients developed complications. Anastomotic leak and peritonitis were the most common complications seen in 6 (12.2). Seven patients (14.28) died in the hospital. The mean survival was 5.47 ± 8.38 months. Upon follow up, survival was significantly longer in older patients (P=0.01). Conclusion: In one-fourth of the patients with advanced stages of cancer, palliative surgery of the pancreatic head and Ampulla of Vater caused complications, and the mean survival rate was less than six months. The results of this study recommend the use of less invasive procedures such as biliary stenting in the advanced stages of the disease. © 2017, Iranian Epidemiological Association. All Rights Reserved.

Item Type: Article
Keywords: Ampullary carcinoma Cancer of pancreas head Complications Survival advanced cancer age distribution anastomosis leakage Article bile duct bypass bypass surgery cancer surgery clinical article follow up gastric bypass surgery human palliative therapy pancreas cancer peritonitis postoperative complication survival rate Vater papilla carcinoma
Divisions:
Page Range: pp. 68-74
Journal or Publication Title: Iranian Journal of Epidemiology
Journal Index: Scopus
Volume: 13
Number: 1
ISSN: 17357489 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/192

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