Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Sezary syndrome, Kaposi sarcoma and generalized dermatophytosis 15 years after sulfur mustard gas exposure

(2012) Sezary syndrome, Kaposi sarcoma and generalized dermatophytosis 15 years after sulfur mustard gas exposure. J Dermatol Case Rep. pp. 86-9. ISSN 1898-7249

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Official URL: http://www.ncbi.nlm.nih.gov/pubmed/23091586

Abstract

BACKGROUND: The relationship between compromised immune system and the development of malignancy, generalized dermatitis, and infection after sulfur mustard gas exposure has been established. MAIN OBSERVATION: We introduce a 58-year-old man with an abrupt, de novo and erythrodermic eruption in 2002 that was previously exposed to sulfur mustard during the Iran - Iraq war in 1987. Six weeks after the onset of diffuse eruption, he developed papules on the glans penis and generalized dermatophytosis. A biopsy of his eruption was consistent with cutaneous T-cell lymphoma/Sezary syndrome. A complete blood count demonstrated leukocytosis, eosinophilia and atypical lymphocytosis. Subsequently, Sezary syndrome was confirmed and T-cell count with increased CD4/CD8 in flow cytometry. The biopsy of his penile papules was consistent with Kaposi's sarcoma. CONCLUSION: These findings suggest a causative relationship between sulfur mustard gas exposure, cutaneous T cell lymphoma and immune compromised state with opportunistic infections.

Item Type: Article
Keywords: Kaposi's sarcoma Sezary syndrome cutaneous T-cell lymphoma genital genotoxins war
Divisions:
Page Range: pp. 86-9
Journal or Publication Title: J Dermatol Case Rep
Journal Index: Pubmed
Volume: 6
Number: 3
Identification Number: https://doi.org/10.3315/jdcr.2012.1109
ISSN: 1898-7249
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/2028

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