Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Efficacy of phospholipidated curcumin in nonalcoholic fatty liver disease: a clinical study

(2019) Efficacy of phospholipidated curcumin in nonalcoholic fatty liver disease: a clinical study. Journal of Asian Natural Products Research. pp. 798-805. ISSN 1028-6020

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Abstract

Curcumin is a safe and dietary phytochemical that can improve different pathophysiologic features of non-alcoholic fatty liver disease (NAFLD). Here, we investigated the efficacy of phospholipidated curcumin supplementation in NAFLD patients. In this single-arm study, 36 patients were recruited. Each patient received three capsules a day (each containing 500 mg of phospholipidated curcumin overall content of curcuminoids per capsule: 100 mg) for a period of 8 weeks. The results indicated that phospholipidated curcumin supplementation reduced NAFLD severity and ameliorated ultrasonographic and biochemical measures (including liver transaminases and lipid profile) associated with disease progression. GRAPHICS .

Item Type: Article
Keywords: Non-alcoholic fatty liver disease curcumin clinical trial dyslipidemia piperine combination phytosomal curcumin insulin-resistance metabolic syndrome metaanalysis management safety acid Plant Sciences Chemistry Pharmacology & Pharmacy
Divisions:
Page Range: pp. 798-805
Journal or Publication Title: Journal of Asian Natural Products Research
Journal Index: ISI
Volume: 21
Number: 8
Identification Number: https://doi.org/10.1080/10286020.2018.1505873
ISSN: 1028-6020
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/2429

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