(2019) Immunogenic and protective antigens of Brucella as vaccine candidates. Comparative Immunology Microbiology and Infectious Diseases. pp. 29-36. ISSN 0147-9571
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Abstract
Brucella is an intracellular pathogen that causes abortion in domestic animals and undulant fever in humans. Due to the lack of a human vaccine against brucellosis, animal vaccines play an important role in the management of animal and human brucellosis for decades. Strain 19, RB51 and Rev1 are the approved Brucella spp. vaccine strains that are most commonly used to protect livestock against infection and abortion. However, due to some disadvantages of these vaccines, numerous studies have been conducted for the development of effective vaccines that could also be used in other susceptible animals. In this review, we compare different aspects of immunogenic antigens that have been a candidate for the brucellosis vaccine.
| Item Type: | Article |
|---|---|
| Keywords: | Brucella Brucellosis Vaccine candidates Immunity outer-membrane protein zn superoxide-dismutase cd8(+) t-cells immune-responses balb/c mice nucleotide-sequence clinical-diagnosis virulence factors in-vivo abortus Immunology Microbiology Veterinary Sciences |
| Divisions: | |
| Page Range: | pp. 29-36 |
| Journal or Publication Title: | Comparative Immunology Microbiology and Infectious Diseases |
| Journal Index: | ISI |
| Volume: | 65 |
| Identification Number: | https://doi.org/10.1016/j.cimid.2019.03.015 |
| ISSN: | 0147-9571 |
| Depositing User: | مهندس مهدی شریفی |
| URI: | http://eprints.bmsu.ac.ir/id/eprint/2448 |
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