Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Investigation of the effects of gamma radiation on plasma levels of Zn, Cu, Mn and Se in nuclear medicine staff

(2019) Investigation of the effects of gamma radiation on plasma levels of Zn, Cu, Mn and Se in nuclear medicine staff. Radioprotection. pp. 47-53. ISSN 0033-8451

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Abstract

We assessed possible changes in the levels of some trace elements among nuclear medicine staff. This study was carried out on 30 nuclear medicine staff and 10 individuals as a control group. After the blood samples were collected, serum levels of trace elements were measured using atomic absorption spectroscopy (AAS). Mean Zn levels in the control group (89.75 + 17.35 mu mol/l) were significantly (p = 0.002) higher than in the exposed group (70.91 + 14.46 mu mol/l). Increased duration of exposure was significantly associated with reduced zinc levels (p = 0.005). Furthermore, the 5-year average dose received was adversely and significantly correlated with zinc concentrations (p = 0.019). No significant difference was observed in the Cu level between control group (93.85 + 25.33 mu mol/l) and staff worker group (85.6+ 21.66 mu mol/l) (p = 0.32). A positive significant correlation was observed between exposure time and reduced Cu levels (p= 0.05). No difference was found in mean Mn and Se levels between both groups according to exposure time. Declined Zn and Cu levels may be considered as one of the possible mechanisms of oxidative damages induced by gammas rays. Therefore, an antioxidant treatment could be recommended for people who work in medical radiation centers.

Item Type: Article
Keywords: gamma radiation zinc manganese copper manganese nuclear medical staff oxidative damage zinc antioxidant copper exposure blood expression serum peroxidation selenium Environmental Sciences & Ecology Public, Environmental & Occupational Health Nuclear Science & Technology Radiology, Nuclear Medicine & Medical Imaging
Divisions:
Page Range: pp. 47-53
Journal or Publication Title: Radioprotection
Journal Index: ISI
Volume: 54
Number: 1
Identification Number: https://doi.org/10.1051/radiopro/2018045
ISSN: 0033-8451
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/2849

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