Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Neuroprotective Agents in the Intensive Care Unit - Neuroprotective Agents in ICU

(2018) Neuroprotective Agents in the Intensive Care Unit - Neuroprotective Agents in ICU. Journal of Pharmacopuncture. pp. 226-240. ISSN 2093-6966

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Abstract

Neuroprotection or prevention of neuronal loss is a complicated molecular process that is mediated by various cellular pathways. Use of different pharmacological agents as neuroprotectants has been reported especially in the last decades. These neuroprotective agents act through inhibition of inflammatory processes and apoptosis, attenuation of oxidative stress and reduction of free radicals. Control of this injurious molecular process is essential to the reduction of neuronal injuries and is associated with improved functional outcomes and recovery of the patients admitted to the intensive care unit. This study reviews neuroprotective agents and their mechanisms of action against central nervous system damages.

Item Type: Article
Keywords: neuroprotection intensive care unit stroke traumatic brain-injury aneurysmal subarachnoid hemorrhage randomized controlled-trial magnesium-sulfate therapy nitric-oxide synthase curcuminoids-piperine combination systemic oxidative stress cerebral-artery occlusion stable nitroxide tempol coa reductase inhibitor Integrative & Complementary Medicine
Divisions:
Page Range: pp. 226-240
Journal or Publication Title: Journal of Pharmacopuncture
Journal Index: ISI
Volume: 21
Number: 4
Identification Number: https://doi.org/10.3831/kpi.2018.21.026
ISSN: 2093-6966
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/2929

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