Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Book Section #449

(2015) CHAPTER 16: Fluoride-Induced Oxidative Stress in the Liver. In: Food and Nutritional Components in Focus. Royal Society of Chemistry, pp. 271-291. ISBN 20451695 (ISSN)

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Abstract

Nowadays, the use of fluorine and fluorinated products in our life style became common and widespread. These products have been utilized by different industries for producing drugs, pesticides, etc. Fluoride is also used to maintain the body's oral health. Although the generalized use of fluorine facilitates our life, the long-term use of fluoride in high concentrations may lead to serious health problems. Among them, fluoride-induced hepatotoxicity is the most common health complication. It is believed that oxidative stress plays a crucial role in fluoride-induced hepatotoxicity. While we cannot remove fluorine and its products from our life, we must prevent or mitigate their adverse effects. In the present review, we discuss fluorine application, its bioavailability, fluoride-induced hepatotoxicity and possible ways to limit the adverse effects. © The Royal Society of Chemistry 2015.

Item Type: Book Section
Divisions:
Title of Book: Food and Nutritional Components in Focus
Page Range: pp. 271-291
Journal Index: Scopus
Volume: 2015-J
Publisher: Royal Society of Chemistry
Identification Number: https://doi.org/10.1039/9781782628507-00271
ISBN: 20451695 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/449

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