Abstract

Autosomal recessive non-syndromic deafness lies or simply NHL is a common inherited disorder of hearing, in Iran, which is inherited in an autosomal recessive hidden (recessive). This means that the disease was transmitted from parent's healthy carriers of the disease to offspring. Our patient is primarily due to the defects (mutations) in genes GJB2 and GJB6. In the world, on average of every 1000 babies, 1 baby is suffering from congenital hearing impairment. More than 60 of the cases are congenital and occur due to genetic factors. In most cases, hearing loss is a multi factorial disorder, which is caused by genetic and environmental factors. Molecular genetics deafness has made significant progress over the past decade. Genes those are responsible for hereditary hearing loss, progressive drawing and copied it. This article focuses on non-syndromic hearing loss, because genes involved in this type of hearing loss, has recently been identified.