Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

A computational fluid-structure interaction model to predict the biomechanical properties of the artificial functionally graded aorta

(2016) A computational fluid-structure interaction model to predict the biomechanical properties of the artificial functionally graded aorta. Bioscience Reports. p. 9. ISSN 0144-8463

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Abstract

In the present study, three layers of the ascending aorta in respect to the time and space at various blood pressures have been simulated. Two well-known commercial finite element (FE) software have used to be able to provide a range of reliable numerical results while independent on the software type. The radial displacement compared with the time as well as the peripheral stress and von Mises stress of the aorta have calculated. The aorta model was validated using the differential quadrature method (DQM) solution and, then, in order to design functionally graded materials (FGMs) with different heterogeneous indexes for the artificial vessel, two different materials have been employed. Fluid-structure interaction (FSI) simulation has been carried out on the FGM and a natural vessel of the human body. The heterogeneous index defines the variation of the length in a function. The blood pressure was considered to be a function of both the time and location. Finally, the response characteristics of functionally graded biomaterials (FGBMs) models with different values of heterogeneous material parameters were determined and compared with the behaviour of a natural vessel. The results showed a very good agreement between the numerical findings of the FGM materials and that of the natural vessel. The findings of the present study may have implications not only to understand the performance of different FGMs in bearing the stress and deformation in comparison with the natural human vessels, but also to provide information for the biomaterials expert to be able to select a suitable material as an implant for the aorta.

Item Type: Article
Keywords: artificial vessel finite element method functionally graded materials thick cylinder human coronary-arteries finite-element hollow cylinders wall stress pressure aneurysm healthy shells plaque flow Biochemistry & Molecular Biology Cell Biology
Divisions:
Page Range: p. 9
Journal or Publication Title: Bioscience Reports
Journal Index: ISI
Volume: 36
Identification Number: https://doi.org/10.1042/bsr20160468
ISSN: 0144-8463
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/4766

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