Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Appraisement Role Of Ubiquinone On Testis Function, Hormonal Parameters And Morphometric Changes Under Oxidative Stress In Rat

(2016) Appraisement Role Of Ubiquinone On Testis Function, Hormonal Parameters And Morphometric Changes Under Oxidative Stress In Rat. Research Journal of Pharmaceutical Biological and Chemical Sciences. pp. 1929-1934. ISSN 0975-8585

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Abstract

It is estimated that male factor of couple infertility is between25 to 50. Oxidative stress is believed to be an important and plausible cause of idiopathic male infertility. First group as control rats with i.p. injection of saline daily. Second group fed on normal diet and supplemented by 10 fructose in drinking water ad libitum with i.p. injection of saline daily. Third group as Fructose fed rats treated with ubiquinone, 10 mg/kg i.p. daily. After 30 days blood serum samples and testis function were analyzed. Testicular Length, weight, capsule thickness, epithelium thickness, diameter of seminiferous tubules, interstitial thickness, connective diameter, TDI, RI, SPI and blood serum Testosterone level analyzed for investigating testicular function. Using ubiquinone in oxidative stress condition can protect testis tissue and improves testicular function.

Item Type: Article
Keywords: Rat Testis Oxidative stress Fructose Ubiquinone coenzyme q(10) high glucose spermatogenesis supplementation inflammation mitochondria infertility Science & Technology - Other Topics
Divisions:
Page Range: pp. 1929-1934
Journal or Publication Title: Research Journal of Pharmaceutical Biological and Chemical Sciences
Journal Index: ISI
Volume: 7
Number: 6
ISSN: 0975-8585
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/4827

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