Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Investigating the effects of using coenzyme Q10 in diabetic like conditions on Phosphor, Magnesium, Iron and ALP of blood serum and diet parameters of adult male rats

(2016) Investigating the effects of using coenzyme Q10 in diabetic like conditions on Phosphor, Magnesium, Iron and ALP of blood serum and diet parameters of adult male rats. Research Journal of Pharmaceutical Biological and Chemical Sciences. pp. 2604-2610. ISSN 0975-8585

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Abstract

High glucose range causes oxidative stress as a result of increased production of reactive oxygen species. Co Q10 inhibits certain enzymes involved in the formation of free radicals and hence attenuates oxidative stress. 45 male adult rats were selected and divided in to three groups. Control rats fed on normal diet ad libitum with i.p. injection of saline daily. Fructose fed control rat group fed on normal diet and supplemented by 10 fructose in drinking water ad libitum with i.p. injection of saline daily. Third group as Fructose fed rats treated with coenzyme Q10 (10 mg/kg i.p. daily). The food and water intake of Fructose Fed group was significantly higher than other two studied groups. The serum P levels were found significantly increased in CoQ10 treated fructose fed rats compared to the fructose fed rats. The serum ALP levels were found decreased in CoQ10 treated fructose fed rats compared to the fructose fed rats. There were no significant changes on serum Mg. using Coenzyme Q10 had protective effects on diabetic like conditions.

Item Type: Article
Keywords: Diabetes Mellitus Co Q10 Biochemical Serum Food Intake Water Intake Rat pathways mellitus Science & Technology - Other Topics
Divisions:
Page Range: pp. 2604-2610
Journal or Publication Title: Research Journal of Pharmaceutical Biological and Chemical Sciences
Journal Index: ISI
Volume: 7
Number: 5
ISSN: 0975-8585
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/4920

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