Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Zeaxanthin and ocular health, from bench to bedside

(2016) Zeaxanthin and ocular health, from bench to bedside. Fitoterapia. pp. 58-66. ISSN 0367-326X

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Cataracts, glaucoma, and age-related macular degeneration are knownas major ocular problems which cause blindness among the elderly population worldwide. Oxidative stress plays an important role in both the initiation and progression of ocular problems and with respect to this; dietary antioxidants can serve as a therapeutic strategy for the improvement of ocular health. Zeaxanthin is known as one of the most important and common xanthophyll carotenoids, possessing multiple therapeutic effects such as strong antioxidant and pro-oxidant behaviour as well as anti-inflammatory effects. A growing body of literature shows that zeaxanthin mitigates ocular problems and suppresses oxidative stress in the Tetinal tissues. This paper aims to critically review the available literature regarding the beneficial effects of zeaxanthin on ocular problems with emphasis on its chemistry, bioavailability, and sources. (C) 2015 ElsevierB.V. All rights reserved.

Item Type: Article
Keywords: Age-related macular degeneration Cataract Ocular problems Oxidative stress Zeaxanthin macular pigment dietary carotenoids beta-carotene lutein cataract risk damage serum antioxidants bioaccessibility Pharmacology & Pharmacy
Page Range: pp. 58-66
Journal or Publication Title: Fitoterapia
Journal Index: ISI
Volume: 109
Identification Number:
ISSN: 0367-326X
Depositing User: مهندس مهدی شریفی

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