Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

HEMODYNAMIC AND STRUCTURAL STUDY OF VARIOUS BIOPROSTHETIC AORTIC HEART VALVE

(2016) HEMODYNAMIC AND STRUCTURAL STUDY OF VARIOUS BIOPROSTHETIC AORTIC HEART VALVE. Biomedical Engineering-Applications Basis Communications. p. 15. ISSN 1016-2372

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Abstract

Simulation of heart and particularly heart valves is amongst the most common and fundamental methods in diagnosis and treatment of heart disorders. Replacement of natural valves with prosthetic valves is a prevalent treatment to valvular damages. The idea of using tissue engineering heart valves is in progress in developing countries. This is because of their unique biocompatibility and biodegradability according to special characteristics and geometries of every single patient's heart. By considering and changing specific parameters for optimization of valve design, one can obtain the most favorable dimensions of the scaffold. So far, there are various studies which have been focused on leaflet stress distribution and deformation, but considering the blood in these studies have been less taken into account. Excellence of considering fluid structure interaction is to provide real physiological condition for heart valve simulation. Simulation of bioprosthetic heart valve with 19 mm diameter for various geometries of leaflets was performed. Hemodynamic parameters such as mean velocity, flow rate, transvalvular pressure drop, effective orifice area, wall shear stresses, and structural parameters like Von Mises were investigated. Results indicated that leaflet with 12 mm height among other geometries is the best case for hemodynamic parameters and Von Mises stress.

Item Type: Article
Keywords: Bioprosthetic heart valve Fluid structure interaction Hemodynamic parameter Stress distribution fluid-structure interaction simulation dynamics model Engineering
Divisions:
Page Range: p. 15
Journal or Publication Title: Biomedical Engineering-Applications Basis Communications
Journal Index: ISI
Volume: 28
Number: 1
Identification Number: https://doi.org/10.4015/s1016237216500083
ISSN: 1016-2372
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/5116

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