Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

The Effect of Ferric Chloride on Superficial Bleeding

(2015) The Effect of Ferric Chloride on Superficial Bleeding. Trauma Monthly. p. 4. ISSN 2251-7464

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Abstract

Background: Controlling superficial bleeding, despite all the progress in surgical science, is still a challenge in some settings. Objectives: This study assesses the hemostatic effects of ferric chloride and compares it with the standard method (suturing technique) to control superficial bleeding. Materials and Methods: In this animal model study, 60 male Wistar rats were used. An incision, 2 cm long and 0.5 cm deep was made on rat skin and the hemostasis time was recorded using ferric chloride at different concentrations (5101525, and 50) and then using a control (i.e. control of bleeding by suturing). The skin tissue was examined for pathological changes. Finally, the obtained data were entered into SPSS (ver.16) and analyzed using Kruskal-Wallis test, Mann-Whitney, Kolmogorov-Smirnov, and Wilcoxon signed ranks test. Results: The hemostasis time for the ferric chloride concentration group was significantly less than for the control group (P < 0.001). Conclusions: Ferric chloride maybe an effective hemostatic agent to control superficial bleeding in rats.

Item Type: Article
Keywords: Hemostasis Suture Bleeding Ferric Chloride topical hemostatic agents arterial thrombosis liver surgery model resection injury Emergency Medicine
Divisions:
Page Range: p. 4
Journal or Publication Title: Trauma Monthly
Journal Index: ISI
Volume: 20
Number: 1
Identification Number: https://doi.org/10.5812/traumamon.18042
ISSN: 2251-7464
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/5535

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