Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

COMPUTATIONAL VACCINOLOGY AND EPITOPE VACCINE DESIGN BY IMMUNOINFORMATICS

(2014) COMPUTATIONAL VACCINOLOGY AND EPITOPE VACCINE DESIGN BY IMMUNOINFORMATICS. Acta Microbiologica Et Immunologica Hungarica. pp. 285-307. ISSN 1217-8950

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Abstract

Human immune system includes variety of different cells and molecules correlating with other body systems. These instances complicate the analysis of the system; particularly in postgenomic era by introducing more amount of data, the complexity is increased and necessity of using computational approaches to process and interpret them is more tangible. Immunoinformatics as a subset of bioinformatics is a new approach with variety of tools and databases that facilitate analysis of enormous amount of immunologic data obtained from experimental researches. In addition to directing the insight regarding experiment selections, it helps new thesis design which was not feasible with conventional methods due to the complexity of data. Considering this features immunoinformatics appears to be one of the fields that accelerate the immunological research progression. In this study we discuss advances in genomics and vaccine design and their relevance to the development of effective vaccines furthermore several division of this field and available tools in each item are introduced.

Item Type: Article
Keywords: immunoinformatics new vaccine design immunology mhc class-i t-cell epitope distinct proteolytic processes antigen-processing pathway allergenic proteins binding peptides comprehensive database immune recognition silico analysis food allergy Immunology Microbiology
Divisions:
Page Range: pp. 285-307
Journal or Publication Title: Acta Microbiologica Et Immunologica Hungarica
Journal Index: ISI
Volume: 61
Number: 3
Identification Number: https://doi.org/10.1556/AMicr.61.2014.3.4
ISSN: 1217-8950
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/5739

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