Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Protective effects of Allium paradoxum against gentamicin-induced nephrotoxicity in mice

(2012) Protective effects of Allium paradoxum against gentamicin-induced nephrotoxicity in mice. Food & Function. pp. 28-29. ISSN 2042-6496

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Abstract

Allium paradoxum (M. Bieb.) G. Don is a locally known vegetable and is utilized for preparation a variety of local foods in northern of Iran. This study was conducted to quantitatively evaluate the recovery effects of A. paradoxum on gentamicin-induced nephrotoxicity in mice. The curative effect of extracts from the aerial parts and bulbs of A. paradoxum against gentamicin-induced renotoxicity in mice was determined. Both extracts at the dose 200 mg kg(-1) day(-1) offered nephroprotective effect by change in the blood urea nitrogen and creatinine. No statistical difference could be obtained in serum creatinine and blood urea nitrogen of bulb-treated mice compared to normal mice. The result show that bulb extract at 200 mg kg(-1) day(-1) has better activity than aerial parts.

Item Type: Article
Keywords: acute-renal-failure Biochemistry & Molecular Biology Food Science & Technology
Divisions:
Page Range: pp. 28-29
Journal or Publication Title: Food & Function
Journal Index: ISI
Volume: 3
Number: 1
Identification Number: https://doi.org/10.1039/c1fo10173k
ISSN: 2042-6496
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/6432

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