Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Non-alcoholic steatohepatitis: An update in pathophysiology, diagnosis and therapy

(2011) Non-alcoholic steatohepatitis: An update in pathophysiology, diagnosis and therapy. Hepatitis Monthly. pp. 74-85. ISSN 1735-143X

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Abstract

Non-alcoholic steatohepatitis (NASH), first described by Ludwig et al, in 1980, is a stage in the wide spectrum of non-alcoholic fatty liver diseases (NAFLDs) and one of the leading causes of chronic liver disease. Several scientists have tried to more distinctly discover and describe different aspects of NASH. In contrast with its counterpart in the NAFLDs-the NAFL-NASH consists of inflammation as well as necrosis in the liver tissue resulting in a poor outcome. NASH is also a known etiology for cryptogenic liver cirrhosis. Evidence suggests that cirrhosis developing due to NASH have a relatively worse outcome compared to that of hepatitis C-related cirrhosis. In this review article, we try to review and present all relevant articles about NASH. (c) 2011 Kowsar M.P.Co. All rights reserved.

Item Type: Article
Keywords: Non - alcoholic steatohepatitis Diagnosis Therapy fatty liver-disease non-alcoholic steatohepatitis placebo-controlled trial insulin-resistance ursodeoxycholic acid hepatic steatosis vitamin-e metabolic syndrome alanine aminotransferase alpha-tocopherol Gastroenterology & Hepatology
Divisions:
Page Range: pp. 74-85
Journal or Publication Title: Hepatitis Monthly
Journal Index: ISI
Volume: 11
Number: 2
ISSN: 1735-143X
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/6598

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