Abstract

Background and Aims: Hepatitis E virus (HEV) is recognized as a common cause of epidemic and sporadic viral hepatitis. HEV outbreaks have been documented in some military forces in the world. The aim of this study was to evaluate anti-HEV antibody in Iranian soldiers. Methods: In a cross-sectional study, 800 soldiers were selected by simple random sampling in Tehran, Iran in 2006. A questionnaire of demographic data was completed and blood samples were obtained for anti-HEV IgG & IgM antibody. Data were analyzed using student t-test and chi-square using SPSS 12. Results: All soldiers were male and their mean age was 19 +/- 1.2. Education level in 553 (69.1) of them was high school diploma or higher. Anti-HEV IgG antibody was positive in only 9 (1.1) of them and IgM was negative in all soldiers. Conclusions: Approximately 98 of soldiers were at risk for HEV infection and before discovering an effective vaccine, preparation of healthy drinking water and personal hygiene education should be considered for prevention of hepatitis E infection.