Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Immunology of HCV and HBV in renal failure and transplantation

(2007) Immunology of HCV and HBV in renal failure and transplantation. Hepatitis Monthly. pp. 93-101. ISSN 1735-143X

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Abstract

Viral hepatitis has a special relationship to renal diseases. Hepatitis B and C viruses (HBV and HCV) infections are more prevalent in renal failure patients than in general population, an important cause of morbidity and mortality of renal failure patients on chronic dialysis and after renal transplantation. The association is largely due to the frequent use of blood products in patients with end-stage kidney diseases and multiple invasive medical procedures to which these patients are exposed. The effects of renal failure on the general health and immune status of patients with renal diseases also make viral hepatitis more difficult to diagnose as well as to manage. Finally, there have been few studies of the natural history and therapy of viral hepatitis in renal failure patients, making conclusions difficult. This paper will review the prevalence, incidence, clinical features, and natural histories of HBV and HCV infections and suggest recommendations for management and therapy in renal failure patients and patients undergoing renal transplantation.

Item Type: Article
Keywords: HBV HCV renal failure renal transplantation immunology hepatitis-c virus hemodialysis-patients b-vaccine dialysis patients allograft recipients alcoholic cirrhosis immune-responses viral-hepatitis liver-disease in-vivo Gastroenterology & Hepatology
Divisions:
Page Range: pp. 93-101
Journal or Publication Title: Hepatitis Monthly
Journal Index: ISI
Volume: 7
Number: 2
ISSN: 1735-143X
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/7185

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