Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Evaluation of latent hemoptysis in Sulfur Mustard injured patients

(2006) Evaluation of latent hemoptysis in Sulfur Mustard injured patients. Environmental Toxicology and Pharmacology. pp. 128-130. ISSN 1382-6689

[img] Text
Evaluation of latent hemoptysis in Sulfur Mustard injured patients..pdf

Download (148kB)

Official URL:


Introduction: Hemoptysis is one of the mustard exposed patients' symptoms. Data from one study on survivors of Sulfur Mustard attacks during World War I had revealed an increased rate of lung cancer among them. Aim of this study was to determine lung HRCT and fluorescence bronchoscopy findings in mustard exposed patients with hemoptysis. Materials and methods: In this cross-sectional study we evaluated 98 patients with protracted hemoptysis in association with history of single exposure to SM. For this mean we used different lung cancer screening tools including HRCT, bronchoscopy (WLB and fluorescence) and pathology (bronchial lavage cytology and biopsy). Results: Mean time of exposure to SM among cases was 15.5 +/- 4.3 (mean +/- S.D.) years ago. Mean age of studied patients was 48.3 +/- 8.2 years. No finding had been found supporting the malignancy in any of cases via imaging and pathological evaluations. Cytological investigation of bronchial lavage for TB (staining and culture) and/or malignancy in all cases was negative. Pathology findings of specimens were: 9 normal, 83 chronic inflammation and 8 squamous metaplasia. Conclusion: Though our findings are in accordance to other studies which are conducted by other Iranian researchers so far, we cannot overlook the risk of lung cancer among SM patients in future. In conclusion, hemoptysis per se in acutely exposed SM patients could not be considered as a valuable evidence of lung malignancy and it is more likely due to other pathologies of respiratory system in SM patients and close monitoring of these patients for early detection of any kind of malignancy is suggested. (c) 2006 Elsevier B.V. All rights reserved.

Item Type: Article
Keywords: chemical warfare mustard gas lung cancer Iran chest HRCT fluorescence bronchoscopy lung-cancer bronchiolitis obliterans world-war-1 veterans chemical weapons gas injury exposure Environmental Sciences & Ecology Pharmacology & Pharmacy Toxicology
Page Range: pp. 128-130
Journal or Publication Title: Environmental Toxicology and Pharmacology
Journal Index: ISI
Volume: 22
Number: 2
Identification Number:
ISSN: 1382-6689
Depositing User: مهندس مهدی شریفی

Actions (login required)

View Item View Item