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Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

In vitro evidence for association between hepatitis C virus infection and insulin signaling pathways: A review

(2014) In vitro evidence for association between hepatitis C virus infection and insulin signaling pathways: A review. Pakistan Journal of Biological Sciences. pp. 601-607. ISSN 10288880 (ISSN)

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Abstract

Hepatitis C virus infection, besides its substantial unfavorable impact on liver health, has several other manifestations, from which we have focused on its associations with insulin resistance and diabetes mellitus in an in vitro setting in this review of the literature. Several epidemiologic studies have already proven the strong association between chronic HCV infection and development of diabetes mellitus. However, attempts to clarifying molecular mechanisms for this association have not made up until recent years. We made a comprehensive review of the literature but we only found 6 studies investigating HCV impact on insulin signaling pathway in an in vitro era. We tried to review and compare the findings of these studies to show what we already know on the issue and what we still need to know. © 2014 Asian Network for Scientific Information.

Item Type: Article
Keywords: Diabetes HCV Hepatitis C virus Insulin signaling pathway insulin complication diabetes mellitus hepatitis C human in vitro study metabolism signal transduction Humans In Vitro Techniques
Divisions:
Page Range: pp. 601-607
Journal or Publication Title: Pakistan Journal of Biological Sciences
Journal Index: Scopus
Volume: 17
Number: 5
Identification Number: https://doi.org/10.3923/pjbs.2014.601.607
ISSN: 10288880 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/76

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