Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Relationship between iron deficiency anemia and febrile seizures

(2010) Relationship between iron deficiency anemia and febrile seizures. Iranian Journal of Child Neurology. pp. 27-30. ISSN 17354668 (ISSN)

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Abstract

Objective Febrile seizure is the most common convulsive disorder in childhood. The role of iron in metabolism of neurotransmitters and carrying oxygen to the brain suggests the possibility of a relationship between iron deficiency anemia and febrile seizures. The aim of this study was to investigate the relationship between iron deficiency anemia and febrile seizures. Materials & Methods This case - control study was performed on 132 cases and 88 controls, aged 9 months to 5 years, from July 2007 to June 2009 in Baqyiatallah Hospital. Patients were selected using simple random sampling. The case group included children with first febrile seizure (core temperature over 38.5°C during seizure) without a central nervous system infection or an acute brain insult. The control group included children suffering from a febrile illness without seizure. Iron deficiency anemia was defined with one of these laboratory indexes: 1) Hemoglobin (Hb) <10.5mg/dl 2) Plasma ferritin <12ng/dl 3) Mean corpuscular volume (MCV) <70 fl. The data collected from patients were analyzed with SPSS.13 software. Results Low plasma ferritin was found in 35 cases (26.5) compared to 26 controls (29.5), low Hb level was found in 4 cases (3) compared to 6 controls (6.8) and low MCV was found in 5 cases (3.8) compared to 6 controls (6.8). There was no significant difference in plasma ferritin , Hb level and MCV indices between the two group. Conclusion Considering the above-mentioned results, there is no relationship between iron deficiency anemia and febrile seizures.

Item Type: Article
Keywords: Children Febrile seizures Iron deficiency anemia ferritin hemoglobin article case control study child computer program controlled study core temperature disease association febrile convulsion ferritin blood level hemoglobin blood level human infant major clinical study mean corpuscular volume preschool child
Divisions:
Page Range: pp. 27-30
Journal or Publication Title: Iranian Journal of Child Neurology
Journal Index: Scopus
Volume: 4
Number: 1
ISSN: 17354668 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/770

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