(2010) The role of nuclear factor-κB in inflammatory lung disease. Inflammation and Allergy - Drug Targets. pp. 197-205. ISSN 18715281 (ISSN)
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Abstract
Nuclear factor-κB (NF-κB) is one of the most important transcription factors; it has a key role in inflammatory and immune responses, cell adhesion, developmental signals, and anti-apoptosis process. Inflammatory lung diseases such as asthma and chronic obstructive pulmonary disease (COPD) are major causes of morbidity and mortality worldwide. In this review, we highlight the role of NF-κB in inflammatory lung disease, the strategies which block the activation of NF- κB, and the therapeutic approaches to treating inflammatory lung disease. © 2010 Bentham Science Publishers Ltd.
| Item Type: | Article |
|---|---|
| Keywords: | Asthma Cell adhesion COPD Inflammatory lung disease NF-κB Therapeutic approach acetylsalicylic acid asbestos deferoxamine dexamethasone ibuprofen immunoglobulin enhancer binding protein indometacin mesalazine mustard gas prednisone salicylate sodium sulindac tepoxalin adult respiratory distress syndrome article chronic obstructive lung disease cystic fibrosis exhaust gas human pneumonia transcription initiation |
| Divisions: | |
| Page Range: | pp. 197-205 |
| Journal or Publication Title: | Inflammation and Allergy - Drug Targets |
| Journal Index: | Scopus |
| Volume: | 9 |
| Number: | 3 |
| Identification Number: | https://doi.org/10.2174/187152810792231904 |
| ISSN: | 18715281 (ISSN) |
| Depositing User: | مهندس مهدی شریفی |
| URI: | http://eprints.bmsu.ac.ir/id/eprint/785 |
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