Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Postoperative back pain following epidural anesthesia: Can dexamethasone help

(2009) Postoperative back pain following epidural anesthesia: Can dexamethasone help. Asian Journal of Pharmaceutics. pp. 261-263. ISSN 09738398 (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Epidural anesthesia (EA) is a central neuraxial block with many applications. Improvements in equipment, drugs and techniques have made it a popular and versatile anesthetic procedure. However, back pain is a common postoperative complaint. We aimed to determine the effect of dexamethasone added to EA to reduce post-epidural anesthesia backache. Fifty-nine patients scheduled undergoing surgery were randomly assigned to two groups: Case group (30 patients) received 300 mg lidocaine (1.5) plus 1/200,000 epinephrine and 4 mg dexamethasone (1CC) for epidural anesthesia, and a control group (29 patients) received 300 mg lidocaine (1.5) with 1/200000 epinephrine and 1CC normal saline (placebo). Patients were visited 12, 24 and 48 hours after operation, and the severity of post-epidural backache was recorded according to a visual analogue scale pain score. In the case group, 29 patients (96.6) had mild back pain, and only 1 patient (3.3) had moderate back pain and none experienced severe back pain post-operatively. In the control group, 19 patients (65.5) had mild backache, 9 patients experienced moderate and 1 had severe backache. Mean backache severity score of the case group was statistically lower than the control group (P = 0.003), after 12 h (P = 0.001), 24 h (P = 0.00) and 48 h (P = 0.002) postoperatively. Dexamethasone addition may be effective in reducing severe to moderate post-epidural anesthesia backache in EA patients.

Item Type: Article
Keywords: Dexamethasone Epidural anesthesia Post-epidural backache adrenalin lidocaine placebo adult aged article backache clinical trial controlled clinical trial controlled study disease severity double blind procedure female human major clinical study male pain assessment postepidural anesthesia backache postoperative pain randomized controlled trial visual analog scale
Divisions:
Page Range: pp. 261-263
Journal or Publication Title: Asian Journal of Pharmaceutics
Journal Index: Scopus
Volume: 3
Number: 3
Identification Number: https://doi.org/10.4103/0973-8398.56309
ISSN: 09738398 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/818

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