Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

The possible role of novel coronavirus 2019 proteins in the development of drugs and vaccines

(2020) The possible role of novel coronavirus 2019 proteins in the development of drugs and vaccines. Journal of Applied Biotechnology Reports. pp. 63-73. ISSN 23221186 (ISSN)

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Abstract

While the world has faced an epidemic disease resulted from severe acute respiratory syndrome coronavirus (SARS-CoV), a disease which has derived from a new coronavirus that has a high contagious power causing severe illness in some individuals that may even lead to death, no vaccine or special effective treatment has been offered yet. By noticing the genetic similarity between Middle East respiratory syndrome coronavirus (MERS) and SARS-CoV viruses with SARS-CoV-2 and especially between SARS-CoV and SARS-CoV-2, the aim of this research was to express the proteins of the SARS-CoV-2 virus including the spike (S), nucleocapsid (N) and other proteins in the virus and their function in entering host cells, virus replication and production on one hand, and developing possible drugs that are effective in treating this coronavirus infection by targeting the above-mentioned proteins. On the other hand, the researchers are looking to offer a possible vaccine to prevent infection with this virus by using the proteins of this virus. © 2020 The Author(s).

Item Type: Article
Keywords: COVID-19 Disease Possible Antiviral Treatments Possible Vaccine SARS-CoV-2 SARS-CoV-2 Viral Proteins
Page Range: pp. 63-73
Journal or Publication Title: Journal of Applied Biotechnology Reports
Journal Index: Scopus
Volume: 7
Number: 2
Identification Number: https://doi.org/10.30491/jabr.2020.230039.1220
ISSN: 23221186 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/8367

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