Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

ADRS due to COVID-19 in midterm pregnancy: successful management with plasma transfusion and corticosteroids

(2020) ADRS due to COVID-19 in midterm pregnancy: successful management with plasma transfusion and corticosteroids. Journal of Maternal-Fetal & Neonatal Medicine. p. 4. ISSN 1476-7058

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Abstract

Background Management of acute respiratory distress syndrome (ARDS) in pregnant women infected with new severe acute respiratory syndrome Corona virus 2 (SARS-CoV2) is a challenging clinical task. Case A 30- year-old woman (gravid 3, parity 2) presented at her 21 and 2/7 weeks gestation (pre pregnancy BMI: 36.1 kg/m(2)), with ARDS caused by SARS-CoV(2)infection. She received lopinavir/ritonavir and azithromycin as well as early methyl prednisolone therapy. Given the persistent hypoxemia despite oxygen therapyvianon rebreather face mask (FiO(2):80), convalescent plasma transfusion was administered that led to a mild clinical improvement as well as decrease in inflammatory markers. Growth of her fetus assessed by obstetric sonography was normal during hospital stay. Conclusion Judicious corticosteroid therapy along with convalescent plasma transfusion to suppress viremia and cytokine storm can lead to favorable outcome in the pregnant women with ARDS caused by SARS-CoV(2)infection without superimposed bacterial infection.

Item Type: Article
Keywords: Pregnancy convalescent plasma transfusion acute respiratory distress syndrome SARS-CoV2 corticosteroid Obstetrics & Gynecology
Page Range: p. 4
Journal or Publication Title: Journal of Maternal-Fetal & Neonatal Medicine
Journal Index: ISI
Identification Number: https://doi.org/10.1080/14767058.2020.1797669
ISSN: 1476-7058
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/8700

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