Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Does sulfur mustard (HD) have an accelerating effect on CABG in HD-exposed people? Is it a link?

(2007) Does sulfur mustard (HD) have an accelerating effect on CABG in HD-exposed people? Is it a link? Clinical and Experimental Medical Letters. pp. 11-13. ISSN 18952089 (ISSN)

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Abstract

Introduction: Sulfur mustard or HD is a chemical warfare agent that causes extensive incapacitating injuries to the skin, respiratory tract and eyes. Cardiac dysrhythmias occurs only in high dose early exposure to HD. Searching medical Databases; no more documents were found addressing cardiac complications of HD. There is only one report concerning long-term cardiac effectsofHD. Material and Methods: Nine war-time (1980s) HD-exposed and 113 non-exposed male patients (aged 39-88 years) have been candidate for CABGs were randomly selected. Data were collected through interview and reviewing of individual patient's documents and then analyzed using SPSS version 11.5 with application of T-test, Chi-square and Fisher's exact test. Results: Mean age was 47.78 (SD±7.26) and 60.48 (SD±9.67) for HD-exposed and non-exposed group respectively. Statistically; there was a significant(P<0.001)differentiation between the two groups. HD-exposed also showed significantly(P<0.001)less physical activities than non-exposed. Relative Risks(RR) for hypercholesterolemia in HD-exposed group were 1.13 (CI 95: 1.06-1.21). Despite minimal differentiations,we didn't statistically find any significant differentiation in other risk factorsof CAD. Discussion: HD exposed subjects suffer from respiratory complications can lower their physical activities. Sedentary life style and hypercholesterolemia we found in HD-exposed group may associate with some degrees of coronary complications. More studies in the field are needed for role out or accepting coronary arteries complications of HD.

Item Type: Article
Keywords: CAD Coronary IHD Revascularization cholesterol mustard gas adult age aged article cigarette smoking controlled study coronary artery bypass graft coronary artery disease diabetes mellitus environmental exposure family history human hypercholesterolemia hypertension hyperthyroidism interview lifestyle major clinical study male medical record review medical research obesity physical activity physical disability respiratory tract disease risk assessment risk factor war
Divisions:
Page Range: pp. 11-13
Journal or Publication Title: Clinical and Experimental Medical Letters
Journal Index: Scopus
Volume: 48
Number: 1
ISSN: 18952089 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/881

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