Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Emerging coronaviruses: first SARS, second MERS and third SARS-CoV-2: epidemiological updates of COVID-19

(2020) Emerging coronaviruses: first SARS, second MERS and third SARS-CoV-2: epidemiological updates of COVID-19. Infez Med. pp. 6-17. ISSN 1124-9390 (Print) 1124-9390

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Emerging coronavirusesfirst SARS, second MERS and third SARSCoV2 epidemiological updates of COVID19.pdf

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Official URL: http://www.ncbi.nlm.nih.gov/pubmed/32532933

Abstract

Since December 2019, the emergence of the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) infection has been reported unexpectedly in Wuhan, China, with staggering infection speed across China and around the world. To date, seven known strains of HCoVs belonging to four genera (i.e., α?, β?, γ, and δ-CoV) have been recognized; the latest one has been identified as the SARS-CoV-2. Although the common transmission routes of SARS-CoV-2 is the respiratory tract, it seems that other routes such as the gastrointestinal tract may be effective for the entry of the virus in the body. Although there are no biological markers to predict the susceptibility of humans to COVID-19, several risk factors have been identified to predict the susceptibility of patients to COVID-19. Initial data revealed that males, pregnant women, elderly, and underlying conditions predispose patients to higher morbidity or mortality and also might be at risk for a severe infection of COVID-19. There is a greater need to better understand the mechanisms and risk factors of transmission routes. To date, despite the whole world effort to review various aspects of SARS-CoV-2, including epidemiology, clinical manifestations, diagnosis, and treatment options, there are still gaps in the knowledge of this disease and many issues remain unclear. Therefore, there is an urgent need for update data on SARS-CoV-2. Here, this study provide the current epidemiological status (transmission routes and risk of transmission, possible origins and source, mortality and morbidity risk, and geographical distribution) of the SARS-CoV-2 in the world in 2020.

Item Type: Article
Keywords: Age Factors Animals Animals, Wild/virology Betacoronavirus/isolation & purification/*pathogenicity Covid-19 China Communicable Diseases, Emerging/*epidemiology/transmission/virology Comorbidity Coronavirus Infections/*epidemiology/transmission/virology Cross Infection/epidemiology/transmission Disease Susceptibility Disease Transmission, Infectious Female Geography, Medical Global Health Host Specificity Humans Infant, Newborn Infectious Disease Transmission, Vertical Male Middle East Respiratory Syndrome Coronavirus/isolation & purification/*pathogenicity Pandemics Pneumonia, Viral/*epidemiology/virology Pregnancy Pregnancy Complications, Infectious/virology Respiratory Distress Syndrome/etiology/mortality Risk Factors SARS Virus/isolation & purification/*pathogenicity SARS-CoV-2 Severe Acute Respiratory Syndrome/*epidemiology/transmission/virology Sex Factors Zoonoses
Page Range: pp. 6-17
Journal or Publication Title: Infez Med
Journal Index: Pubmed
Volume: 28
Number: suppl
ISSN: 1124-9390 (Print) 1124-9390
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/9074

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