Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Estimate of the Basic Reproduction Number for COVID-19: A Systematic Review and Meta-analysis

(2020) Estimate of the Basic Reproduction Number for COVID-19: A Systematic Review and Meta-analysis. J Prev Med Public Health. pp. 151-157. ISSN 1975-8375 (Print) 1975-8375

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Official URL: http://www.ncbi.nlm.nih.gov/pubmed/32498136

Abstract

OBJECTIVES: The outbreak of coronavirus disease 2019 (COVID-19) is one of the main public health challenges currently facing the world. Because of its high transmissibility, COVID-19 has already caused extensive morbidity and mortality in many countries throughout the world. An accurate estimation of the basic reproduction number (R0) of COVID-19 would be beneficial for prevention programs. In light of discrepancies in original research on this issue, this systematic review and meta-analysis aimed to estimate the pooled R0 for COVID-19 in the current outbreak. METHODS: International databases (including Google Scholar, Science Direct, PubMed, and Scopus) were searched to identify studies conducted regarding the R0 of COVID-19. Articles were searched using the following keywords: "COVID-19" and "basic reproduction number" or "R0." The heterogeneity among studies was assessed using the I2 index, the Cochran Q test, and T2. A random-effects model was used to estimate R0 in this study. RESULTS: The mean reported R0 in the identified articles was 3.38±1.40, with a range of 1.90 to 6.49. According to the results of the random-effects model, the pooled R0 for COVID-19 was estimated as 3.32 (95 confidence interval, 2.81 to 3.82). According to the results of the meta-regression analysis, the type of model used to estimate R0 did not have a significant effect on heterogeneity among studies (p=0.81). CONCLUSIONS: Considering the estimated R0 for COVID-19, reducing the number of contacts within the population is a necessary step to control the epidemic. The estimated overall R0 was higher than the World Health Organization estimate.

Item Type: Article
Keywords: Basic Reproduction Number/*statistics & numerical data Betacoronavirus Covid-19 Coronavirus Infections/*epidemiology/transmission Global Health Humans Pandemics Pneumonia, Viral/*epidemiology/transmission SARS-CoV-2 Basic reproduction number Meta-analysis Outbreak Public health material presented in this paper.
Page Range: pp. 151-157
Journal or Publication Title: J Prev Med Public Health
Journal Index: Pubmed
Volume: 53
Number: 3
Identification Number: https://doi.org/10.3961/jpmph.20.076
ISSN: 1975-8375 (Print) 1975-8375
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/9082

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