Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

The risk factors and related hospitalizations for cases with positive and negative COVID-19 tests: A case-control study

(2021) The risk factors and related hospitalizations for cases with positive and negative COVID-19 tests: A case-control study. Int Immunopharmacol. p. 107894. ISSN 1567-5769 (Print) 1567-5769

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Abstract

BACKGROUND: The aim of this study was to evaluate the risk factors for hospitalizations of cases with positive and negative COVID-19 tests. METHODS: In this case-control study, the case and control groups consisted of 292 COVID-19 patients and 296 non-COVID-19 patients. Patients who referred to a reference laboratory in Tehran (Iran) in March 2020 were selected and interviewed. The patients were contacted by telephone and data were recorded through a questionnaire. RESULTS: The sample of this study consisted of 588 patients (349 59% females, 239 41% males) with a mean age of 42 ± 15. The results of this study showed that comorbidities like diabetes (OR = 7.42), hypertension (OR = 4.85), asthma and respiratory diseases (OR = 5.64) in addition to symptoms including fever (OR = 6.67), chills (OR = 11.2), anorexia (OR = 11.3), dyspnea (OR = 4.8), weakness and lethargy (OR = 5.7) were the most predictive variables for hospitalization of non-COVID-19 cases. Furthermore, demographical variables like male gender (OR = 3.71), high age (>50; OR = 3.12), BMI (>25; OR = 2.37), travel (OR = 2.79), comorbidities including diabetes (OR = 5.26), hypertension (OR = 3.7) and underlying immunosuppressant patients receiving corticosteroid therapy (OR = 3.62) in addition to symptoms like anorexia OR = 2.55 and dyspnea (OR = 6.99) tend to increase the risk of hospital admission in COVID-19 patients, suggesting their predictive values for hospitalization of COVID-19 patients. CONCLUSION: Our results indicated that different factors tend to increase the odds of hospital admission in patients with positive and negative COVID-19 tests, suggesting their predictive values for hospitalization.

Item Type: Article
Keywords: Adolescent Adult Aged Aged, 80 and over COVID-19/*diagnosis/mortality/therapy *COVID-19 Testing Comorbidity Female Hospital Mortality *Hospitalization Humans Iran Male Middle Aged Predictive Value of Tests Prognosis Retrospective Studies Risk Assessment Risk Factors Time Factors Young Adult Covid-19 Co-Morbidities Hospitalization Policymaking
Page Range: p. 107894
Journal or Publication Title: Int Immunopharmacol
Journal Index: Pubmed
Volume: 98
Identification Number: https://doi.org/10.1016/j.intimp.2021.107894
ISSN: 1567-5769 (Print) 1567-5769
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/9370

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