Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Synthesis and Evaluation of Radical Scavenging Activity of (Pyrazole-3,5-Diyl)Bis(Ethene-2,1-Diyl))Bis(2-Methoxyphenol) Derivatives

(2021) Synthesis and Evaluation of Radical Scavenging Activity of (Pyrazole-3,5-Diyl)Bis(Ethene-2,1-Diyl))Bis(2-Methoxyphenol) Derivatives. Polycyclic Aromatic Compounds. p. 11. ISSN 1040-6638

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Abstract

In this article, a series of curcumin based derivatives are synthesized and characterized by several characterization methods, including H-1 NMR and FT-IR, MASS and CHN elemental analysis. Radical scavenging activity of the synthesized compounds is evaluated and it was observed that the compounds have radical scavenging properties. For studying the radical scavenging activity of the synthesized compounds, the 1,l-diphenyl-2-picryl-hydrazyl (DPPH) method was applied. The activity of 4,4'-((1E,1'E)-(1-(p-tolyl)-1H-pyrazole-3,5-diyl)bis(ethene-2,1-diyl))bis(2-methoxyphenol) in reaction with DPPH was better than that of curcumin and more active in the studied tests.

Item Type: Article
Keywords: Curcumin organic synthesis radical scavenging activity (pyrazole-3 5-diyl)bis(ethene-2 1-diyl))bis(2-methoxyphenol) curcumin analogs in-vitro antioxidant rat nanoparticles inhibition stability prospects protects Chemistry
Page Range: p. 11
Journal or Publication Title: Polycyclic Aromatic Compounds
Journal Index: ISI
Identification Number: https://doi.org/10.1080/10406638.2021.2022725
ISSN: 1040-6638
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/9579

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