Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

ROLE AND APPLICATION OF STEM CELLS IN DENTAL REGENERATION: A COMPREHENSIVE OVERVIEW

(2021) ROLE AND APPLICATION OF STEM CELLS IN DENTAL REGENERATION: A COMPREHENSIVE OVERVIEW. Excli Journal. pp. 454-489. ISSN 1611-2156

[img] Text
ROLE AND APPLICATION OF STEM CELLS IN DENTAL REGENERATION A COMPREHENSIVE OVERVIEW.pdf

Download (1MB)

Official URL: http://apps.webofknowledge.com/InboundService.do?F...

Abstract

Recently, a growing attention has been observed toward potential advantages of stem cell (SC)-based therapies in regenerative treatments. Mesenchymal stem/stromal cells (MSCs) are now considered excellent candidates for tissue replacement therapies and tissue engineering. Autologous MSCs importantly contribute to the state-of-theart clinical strategies for SC-based alveolar bone regeneration. The donor cells and immune cells play a prominent role in determining the clinical success of MSCs therapy. In line with the promising future that stem cell therapy has shown for tissue engineering applications, dental stem cells have also attracted the attention of the relevant researchers in recent years. The current literature review aims to survey the variety and extension of SC-application in tissue-regenerative dentistry. In this regard, the relevant English written literature was searched using keywords: "tissue engineering", "stem cells", "dental stem cells", and "dentistry strategies". According to the available database, SCs application has become increasingly widespread because of its accessibility, plasticity, and high proliferative ability. Among the growing recognized niches and tissues containing higher SCs, dental tissues are evidenced to be rich sources of MSCs. According to the literature, dental SCs are mostly present in the dental pulp, periodontal ligament, and dental follicle tissues. In this regard, the present review has described the recent findings on the potential of dental stem cells to be used in tissue regeneration.

Item Type: Article
Keywords: Dental stem cells regeneration stem cell therapy exfoliated deciduous teeth bone morphogenetic proteins human periodontal-ligament growth factor-bb in-vitro odontogenic differentiation osteogenic differentiation stem/progenitor cells apical papilla pulp complex Life Sciences & Biomedicine - Other Topics
Page Range: pp. 454-489
Journal or Publication Title: Excli Journal
Journal Index: ISI
Volume: 20
Identification Number: https://doi.org/10.17179/excli2021-3335
ISSN: 1611-2156
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/9740

Actions (login required)

View Item View Item