Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Clinical and laboratory status of enteric symptomatic amebiasis in patients

(2011) Clinical and laboratory status of enteric symptomatic amebiasis in patients. Trauma Monthly. pp. 175-180. ISSN 22517464 (ISSN)

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Aims: Amebiasis is endemic in Iran and its infection rate is about 8-40. Considering the diagnostic problems, studies on amebiasis have been sparse and little study has been performed compared to other countries. This study was done with the aim of assessing the clinical and laboratory characteristics of enteric symptomatic amebiasis in one of Tehran's hospitals. Materials & Methods: This cross-sectional analytical survey was performed on 159 patients who referred to the GI clinic of one of Tehran's hospitals who were selected by Census sampling method, between March and June 2009. Stool exam and serologic assessment was performed for all included patients. Ten days after treatment, stool and serology tests were requested again with the same sampling conditions. Data was analyzed by descriptive statistical methods and Chi square test with SPSS 14 software. Results: Highest and lowest frequency of clinical symptoms belonged to dysentery and vomiting. According to the first stool exam, 37 patients were infected with Entamoeba histolytica/dispar. Among them, 18 patients had cysts, 12 patients had trophozoites and 7 patients had both. After treatment, stool exam was positive only in two patients who had cysts. Conclusion: Stool exam is a very poor diagnostic test for Entamoeba histolytica and more accurate methods such as serology or antigen test or PCR are recommended for the diagnosis of Entamoeba histolytica which is the only pathogen type.

Item Type: Article
Keywords: Amebiasis Clinical symptoms Laboratory findings Serologic exam Stool exam antigen detection article clinical feature controlled study cross-sectional study dysentery Entamoeba dispar Entamoeba histolytica feces analysis human Iran major clinical study polymerase chain reaction serology symptomatology trophozoite vomiting
Page Range: pp. 175-180
Journal or Publication Title: Trauma Monthly
Journal Index: Scopus
Volume: 16
Number: 3
ISSN: 22517464 (ISSN)
Depositing User: مهندس مهدی شریفی

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