Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Auto-transplantation of whole rat ovary in different transplantation sites

(2017) Auto-transplantation of whole rat ovary in different transplantation sites. Veterinary Research Forum. pp. 275-280. ISSN 2008-8140

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This study was carried out to assess the different ovarian transplantation sites after shorttime autografting. Female rats were randomized into five groups, with six rats in each group, including control (intact), cervical subcutaneous transplanted (CST), back subcutaneous transplanted (BST), subfascial transplanted (SFT) and intramuscular transplanted (IMT) groups. In all experimental groups, the right ovary was removed and transplanted into different sites. After three weeks, ovaries were removed for morphology assessment, follicular counting and the rates of corpus luteum (CL) and cyst formation. Transplanted ovaries in BST and SFT groups were full of cysts and did not have sufficient numbers of intact follicles and were excluded from experiments. In IMT and CST groups, re-anastomosis, follicular development and good homogeneity of the stromal tissue were seen. However, the difference in intact antral follicles between CST (7.92 +/- 0.02) and CST-Op (opposite ovary of CST group) (30.99 +/- 0.03) was significant as well as the difference between CST (7.92 +/- 0.02) and control (10.08 +/- 0.01) groups. In addition, the number of intact primordial follicles in the CST-Op (16.58 +/- 0.02) group was significantly less than that of the control (40.40 +/- 0.03) group. Interestingly, the number of CL was significantly increased in the CST-Op (11.71 +/- 0.01) and IMT-Op (9.16 +/- 0.02) groups compared to the control and experimental groups. Although both intramuscular and subcutaneous sites effectively preserved ovarian follicles after three weeks, cervical subcutaneous site was better suited for auto-transplantation in rat. (C) 2017 Urmia University. All rights reserved.

Item Type: Article
Keywords: Auto-transplantation Rat Transplantation site Whole ovary back muscle fertility preservation tissue-transplantation oocytes Veterinary Sciences Zoology
Page Range: pp. 275-280
Journal or Publication Title: Veterinary Research Forum
Journal Index: ISI
Volume: 8
Number: 4
ISSN: 2008-8140
Depositing User: مهندس مهدی شریفی

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