Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Flavanones: Citrus phytochemical with health-promoting properties

(2017) Flavanones: Citrus phytochemical with health-promoting properties. Biofactors. pp. 495-506. ISSN 0951-6433

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Citrus fruit and juices represent one of the main sources of compounds with a high potential for health promoting properties. Among these compounds, flavanones (such as hesperetin, naringenin, eriodictyol, isosakuranetin, and their respective glycosides), which occur in quantities ranging from approximate to 180 to 740 mg/L (depending on the Citrus species and cultivar) are responsible for many biological activities. These compounds support and enhance the body's defenses against oxidative stress and help the organism in the prevention of cardiovascular diseases, atherosclerosis, and cancer. Moreover, among other properties, they also show anti-inflammatory, antiviral, and antimicrobial activities. This review analyzes the biochemistry, pharmacology, and biology of Citrus flavanones, emphasizing the occurrence in Citrus fruits and juices and their bioavailability, structure-function correlations and ability to modulate signal cascades both in vitro and in vivo. (c) 2017 BioFactors, 43(4):495-506, 2017

Item Type: Article
Keywords: flavanones biosynthesis and metabolism health promoting properties anti-inflammatory activity anticholesterolemic activity degenerative diseases orange juice (poly)phenols o-glycosyl flavonoids nf-kappa-b radical-scavenging activity human serum-albumin l. osbeck juice in-vitro down-regulation aurantium l. hesperidin Biochemistry & Molecular Biology Endocrinology & Metabolism
Page Range: pp. 495-506
Journal or Publication Title: Biofactors
Journal Index: ISI
Volume: 43
Number: 4
Identification Number:
ISSN: 0951-6433
Depositing User: مهندس مهدی شریفی

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