Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Depression and Hypothyroidism in a Population-Based Study of Iranian Women

(2016) Depression and Hypothyroidism in a Population-Based Study of Iranian Women. Romanian Journal of Internal Medicine. pp. 217-221. ISSN 1582-3296

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Background. Recent biochemical and physiological investigations have focused on the fundament of mood disorders in thyroid dysfunction. The present study aimed to address depressive disorder in a sample of Iranian hypothyroid women compared to euthyroid individuals. Methods. Thirty consecutive hypothyroid female patients aged 25 to 40 years who referred to the Endocrinology and Metabolism Clinic at Rasoul-e-Akram Hospital in Tehran within a four-month period in 2015 were assessed. Thirty healthy euthyroid subjects matched for sex, age, and educational level were selected as the control. For assessment of depression status, Depression Anxiety Stress Scale-21 (DASS-21) was employed. Results. The study showed higher mean depression score in hypothyroid patients when compared to euthyroid ones (13.8 +/- 9.5 versus 5.8 +/- 5.2, p = 0.010). No significant association was revealed between mean depression score and patients' education level (p = 0.627), age (p = 0.967), occupation status (p = 0.211), and marital status (p = 0.556). Conclusion. Hypothyroid women are predisposed to depressive symptoms independent of their baseline demographic and socioeconomic characteristics.

Item Type: Article
Keywords: depression hypothyroidism symptom euthyroid mood disorder biochemical marker pituitary-thyroid-axis transthyretin disorders csf General & Internal Medicine
Page Range: pp. 217-221
Journal or Publication Title: Romanian Journal of Internal Medicine
Journal Index: ISI
Volume: 54
Number: 4
Identification Number:
ISSN: 1582-3296
Depositing User: مهندس مهدی شریفی

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