Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

The lack of association between idiopathic hirsutism and metabolic disturbances: Iranian PCOS Prevalence Study

(2013) The lack of association between idiopathic hirsutism and metabolic disturbances: Iranian PCOS Prevalence Study. Gynecological Endocrinology. pp. 821-825. ISSN 0951-3590

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Background: Idiopathic hirsutism (IH) is a condition diagnosed after other hirsutisnn related is ruled out. Its definition diagnosis had a dynamic process along with improving the understanding of the various androgen excess disorders. There is uncertainty regarding its health impact and its long-term metabolic consequences. We aimed to compare metabolic syndrome (Mets) and insulin resistance (IR) of Iranian women with IH and a group of healthy controls in a large community-based study. Methods: Anthropometric measurements, biochemical parameters, Mets (using Joint Interim Statement criteria) and IR (estimated by the homeostasis model assessment), were compared between 101 women with IH and 423 healthy controls recruited from among 1126 reproductive aged women. Results: There was a statistically significant difference between the BMI of women with IN in comparison to normal control (27.7 versus 26.7 kg/m(2), p = 0.02); however, the prevalence of android adiposity was similar (26.7 and 24.3, respectively). The age and BMI adjusted prevalence of Mets and IR are similar in women with IH and controls (30 versus 23.9 and 25.7 versus 22.5, respectively). Conclusion: There will be no need for additional cardiometabolic evaluations for women with IH, later in life.

Item Type: Article
Keywords: Android adiposity community based study idiopathic hirsutism insulin resistance metabolic syndrome polycystic-ovary-syndrome growth-factor-i insulin-resistance waist circumference androgen excess women hyperandrogenism indexes polymorphisms testosterone Endocrinology & Metabolism Obstetrics & Gynecology
Page Range: pp. 821-825
Journal or Publication Title: Gynecological Endocrinology
Journal Index: ISI
Volume: 29
Number: 9
Identification Number:
ISSN: 0951-3590
Depositing User: مهندس مهدی شریفی

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