Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Seroepidemiology of HBV Infection in South-East of Iran; A Population Based Study

(2012) Seroepidemiology of HBV Infection in South-East of Iran; A Population Based Study. Iranian Red Crescent Medical Journal. pp. 283-288. ISSN 2074-1804

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Background: Hepatitis B virus (HBV) infection is a major risk factor of cirrhosis and hepatocellular carcinoma affecting billions of people globally. Since information on its prevalence in general population is mandatory for formulating effective policies, this population based serological survey was conducted in Sistan and Baluchistan, where no previous epidemiological data were available. Methods: Using random cluster sampling 3989 healthy subjects were selected from 9 districts of Sistan and Baluchistan Province in southeastern Iran. The subjects' age ranged from 6 to 65 years old. Serum samples were tested for HBcAb, HBsAg. Screening tests were carried out by the third generation of ELISA. Various risk factors were recorded and multivariate analysis was performed. Results: The prevalence of HBsAg and HBcAb in Sistan and Baluchistan was 3.38 (95 CI 2.85; 3.98) and 23.58 (95 CI 22.29; 24.93) respectively. We found 8 cases of positive anti-HDV antibody. Predictors of HBsAg or HBcAb in multivariate analysis were age, marital status and addiction. Conclusion: The rate of HBV infection in Sistan and Baluchistan was higher than other parts of Iran. Approximately 25 of general population in this province had previous exposure to HBV and 3 were HBsAg carriers. Intrafamilial and addiction were major routes of HBV transmission in this province.

Item Type: Article
Keywords: Epidemiology Hepatitis HBV Iran hepatitis-b-virus hemodialysis-patients seroprevalence province transmission General & Internal Medicine
Page Range: pp. 283-288
Journal or Publication Title: Iranian Red Crescent Medical Journal
Journal Index: ISI
Volume: 14
Number: 5
ISSN: 2074-1804
Depositing User: مهندس مهدی شریفی

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