Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

The human immune system toward staphylococcus aureus

(2020) The human immune system toward staphylococcus aureus. Open Microbiology Journal. pp. 164-170. ISSN 18742858 (ISSN)

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The immune system is responsible for protecting the host from pathogens, and it has evolved to deal with these pathogens. On the other hand, the co-evolution of pathogenic bacteria with hosts has led to the rise of an array of virulence genes that enable pathogen bacteria to evade or modulate the immune system. Staphylococcus aureus is a significant pathogen of humans that encodes several virulence factors that can modulate or evade from the innate and adaptive arm of the immune system. Overall, the immune reaction toward S. aureus contributes to stimulate innate and adaptive reactions. A profound understanding of the immune response to S. aureus infections will be critical for the development of vaccines and novel therapies. In this review, we summarized and discussed the novel information about the human immune system against S. aureus. © 2020 Mirzaei et al.

Item Type: Article
Keywords: Adaptive immunity Immune system Innate immunity Methicillin-resistant S. aureus Pathogen Staphylococcus aureus CD36 antigen CD4 antigen CD8 antigen complement component C3b complement component C3d cytotoxic T lymphocyte antigen 4 gamma interferon interleukin 10 interleukin 17 interleukin 23 interleukin 6 leukocidin myeloid differentiation factor 88 nitric oxide transcription factor AP 1 virulence factor antibody affinity antigen presenting cell antimicrobial activity apoptosis bacterial infection cellular immunity cytokine production dendritic cell extracellular matrix germination homeostasis human human cell Human immunodeficiency virus infection humoral immunity immune response keratinocyte macrophage melanocyte memory cell methicillin resistant Staphylococcus aureus mouse natural killer T cell neutrophil nonhuman osteomyelitis peptide synthesis phagocyte phagocytosis priority journal Review Staphylococcus infection T lymphocyte toxic shock syndrome vaccination
Page Range: pp. 164-170
Journal or Publication Title: Open Microbiology Journal
Journal Index: Scopus
Volume: 14
Number: 1
Identification Number:
ISSN: 18742858 (ISSN)
Depositing User: مهندس مهدی شریفی

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