Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Fabrication of an electrochemical mesalazine sensor based on ZIF-67

(2020) Fabrication of an electrochemical mesalazine sensor based on ZIF-67. Measurement. p. 7. ISSN 0263-2241

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This paper describes the application of ZIF-67 nanoparticles for carbon paste electrode (CPE) modification for sensitive voltammetric detection of mesalazine (MSA). The characterization of as-synthesized ZIF-67 nanoparticles was investigated by different techniques. Furthermore, the electrochemical behavior of the modified CPE (MCPE) was investigated using EIS (electrochemical impedance spectroscopy) and CV (cyclic voltammetry) methods. The results showed an irreversible oxidation peak for MSA around 0.540 V vs. the Ag/AgCl reference electrode. The curve of the peak current of differential pulse voltammetry (DPV) vs MSA concentration was linear in the range of 0.03-50 mu M with a detection limit of 0.01 mu M. The prepared sensor presents good repeatability with acceptable relative standard deviation (RSD) values. Finally, the prepared electrode was successfully used in human serum and urine as real samples. (C) 2020 Elsevier Ltd. All rights reserved.

Item Type: Article
Keywords: Electrochemical sensor Mesalazine Modified carbon paste electrode ZIF-67 metal-organic framework 5-aminosalicylic acid mesalamine sulfasalazine metaanalysis budesonide nanosheets reduction oxidation electrode Engineering Instruments & Instrumentation
Page Range: p. 7
Journal or Publication Title: Measurement
Journal Index: ISI
Volume: 165
Identification Number:
ISSN: 0263-2241
Depositing User: مهندس مهدی شریفی

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