Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Maternal death due to COVID-19

(2020) Maternal death due to COVID-19. American Journal of Obstetrics and Gynecology. p. 16. ISSN 0002-9378

[img] Text
Maternal death due to COVID-19.pdf

Download (1MB)

Official URL:


BACKGROUND: Despite 2.5 million infections and 169,000 deaths worldwide (as of April 20, 2020), no maternal deaths and only a few pregnant women afflicted with severe respiratory morbidity have been reported to be related to COVID-19 disease. Given the disproportionate burden of severe and fatal respiratory disease previously documented among pregnant women following other coronavirus-related outbreaks (SARS-CoV in 2003 and MERS-CoV in 2012) and influenza pandemics over the last century, the absence of reported maternal morbidity and mortality with COVID-19 disease is unexpected. OBJECTIVE: To describe maternal and perinatal outcomes and death in a case series of pregnant women with COVID-19 disease. STUDY DESIGN: We describe here a multiinstitution adjudicated case series from Iran that includes 9 pregnant women diagnosed with severe COVID-19 disease in their second or third trimester. All 9 pregnant women received a diagnosis of SARS-CoV-2 infection by reverse transcription polymerase chain reaction nucleic acid testing. Outcomes of these women were compared with their familial/household members with contact to the affected patient on or after their symptom onset. All data were reported at death or after a minimum of 14 days from date of admission with COVID-19 disease. RESULTS: Among 9 pregnant women with severe COVID-19 disease, at the time of reporting, 7 of 9 died, 1 of 9 remains critically ill and ventilator dependent, and 1 of 9 recovered after prolonged hospitalization. We obtained self-verified familial/household cohort data in all 9 cases, and in each and every instance, maternal outcomes were more severe compared with outcomes of other high- and low-risk familial/household members (n = 33 members for comparison). CONCLUSION: We report herein maternal deaths owing to COVID-19 disease. Until rigorously collected surveillance data emerge, it is prudent to be aware of the potential for maternal death among pregnant women diagnosed as having COVID-19 disease in their second or third trimester.

Item Type: Article
Keywords: coronavirus disease in pregnancy COVID-19 lower respiratory infections in pregnancy maternal death maternal mortality maternal respiratory morbidity pregnancy respiratory failure with COVID-19 SARS CoV-2 virus respiratory syndrome pregnancy coronavirus Obstetrics & Gynecology
Page Range: p. 16
Journal or Publication Title: American Journal of Obstetrics and Gynecology
Journal Index: ISI
Volume: 223
Number: 1
Identification Number:
ISSN: 0002-9378
Depositing User: مهندس مهدی شریفی

Actions (login required)

View Item View Item