Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Factors Associated with Mortality in COVID-19 Patients: A Systematic Review and Meta-Analysis

(2020) Factors Associated with Mortality in COVID-19 Patients: A Systematic Review and Meta-Analysis. Iranian Journal of Public Health. pp. 1211-1221. ISSN 2251-6085

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Background: The current study aimed to identify effective factors on the death among COVID-19 patients. Methods: All articles published in the period Jan 1, 2020, to Mar 23, 2020, written in English and reporting factors associated with COVID-19 mortality were reviewed. The random-effects model with 95 CI was used to calculate the pooled Odds Ratio (OR) and Hazard Ratio (HR). Data were analyzed using Stata ver.11.0. Results: The older age OR: 1.21(1.10-1.33) and male gender OR: 1.41(1.04-1.89) were most prone to death due to COVID-19. The Comorbidity with some chronic diseases such as Diabetes type2 OR: 2.42(1.06-5.52), Hypertension OR: 2.54(1.21-5.32), Kidney disorder OR: 2.61(1.22-5.60), Respiratory disorder 3.09 (1.39-6.88) and Heart diseases OR: 4.37 (1.13-16.90) can increase the risk of COVID19 mortality. Conclusion: Infection with COVID-19 is associated with substantial mortality mainly in older patients with comorbidities. We found the significant effect of age, gender and comorbidities such as Diabetes Mellitus, Hypertension, Kidney disorders and Heart diseases on the risk of death in patients with COVID-19. The factors associated with mortality found in this research can help to recognize patients with COVID-19 who are at higher risk of a poor prognosis. Monitoring these factors can serve to give early warning for the appropriate interventions.

Item Type: Article
Keywords: Coronavirus disease 2019 SARS-CoV-2 COVID-19 Mortality Comorbidities respiratory syndrome risk infection severity Public, Environmental & Occupational Health
Page Range: pp. 1211-1221
Journal or Publication Title: Iranian Journal of Public Health
Journal Index: ISI
Volume: 49
Number: 7
ISSN: 2251-6085
Depositing User: مهندس مهدی شریفی

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