Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

The Primary Outcomes and Epidemiological and Clinical Features of Coronavirus Disease 2019 (COVID-19) in Iran

(2021) The Primary Outcomes and Epidemiological and Clinical Features of Coronavirus Disease 2019 (COVID-19) in Iran. Adv Exp Med Biol. pp. 199-210. ISSN 0065-2598 (Print) 0065-2598

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AIM: We aimed to describe the epidemiological and clinical characteristics of Iranian patients with COVID-19. METHODS: In this single-center and retrospective study, patients with confirmed COVID-19 infections were enrolled. Univariate and multivariate logistic regression methods were used to explore the risk factors associated with outcomes. RESULTS: Of 179 patients with confirmed COVID-19 infection, 12 remained hospitalized at the end of the study and 167 were included in the final analysis. Of these, 153 (91.6) were discharged and 14 (8.38) died in hospital. Approximately half (50.9) of patients suffered from a comorbidity, with diabetes or coronary heart disease being the most common in 20 patients. The most common symptoms on admission were fever, dyspnea, and cough. The mean durations from first symptoms to hospital admission was 8.64 ± 4.14 days, whereas the mean hospitalization time to discharge or death was 5.19 ± 2.42 and 4.35 ± 2.70 days, respectively. There was a significantly higher age in non-survivor patients compared with survivor patients. Multivariate regression showed increasing odds ratio (OR) of in-hospital death associated with respiratory rates >20 breaths/min (OR: 5.14, 95 CI: 1.19-22.15, p = 0.028) and blood urea nitrogen (BUN) >19 mg/dL (OR: 4.54, 95 CI: 1.30-15.85, p = 0.017) on admission. In addition, higher respiratory rate was associated with continuous fever (OR: 4.08, 95 CI: 1.18-14.08, p = 0.026) and other clinical symptoms (OR: 3.52, 95 CI: 1.05-11.87, p = 0.04). CONCLUSION: The potential risk factors including high respiratory rate and BUN levels could help to identify COVID-19 patients with poor prognosis at an early stage in the Iranian population.

Item Type: Article
Keywords: *Covid-19 Comorbidity Hospitalization Humans Iran/epidemiology Retrospective Studies Risk Factors SARS-CoV-2 Blood urea nitrogen Covid-19 Iran Mers Respiratory rate Sars
Page Range: pp. 199-210
Journal or Publication Title: Adv Exp Med Biol
Journal Index: Pubmed
Volume: 1321
Identification Number:₁₇
ISSN: 0065-2598 (Print) 0065-2598
Depositing User: مهندس مهدی شریفی

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