Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

A review of herbal medicine: Silybum marianum

(2004) A review of herbal medicine: Silybum marianum. Journal of Medicinal Plants. 14-24+XII. ISSN 16840240 (ISSN)

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Silymarin is the seed extract of silybum marianum herbal medicine widely used for liver and bilary abnormality in China and several European country. It protect liver from several toxicity including acetaminophen, alcohol and amanita mashrom poisoning. Silymarin is composed of several flavonoids with antioxidative, anti-inflammatory and increasing cellular glutathion level properties. Although several experimental and clinical investigation indicating its efficacy against liver and prostate cancer, cisplatin induced kidney toxicity, and type II diabetes, but further clinical study need for its clinical use. However no adverse effect is reported by its chronic use or its administration to children, or pregnancy and lactation women.

Item Type: Article
Keywords: Antioxidant Herbal medicine Liver Silymarin alcohol flavonoid glutathione paracetamol Amanita phalloides antioxidant activity drug efficacy human liver cancer liver disease liver protection mushroom poisoning nephrotoxicity non insulin dependent diabetes mellitus prostate cancer review side effect Silybum marianum
Page Range: 14-24+XII
Journal or Publication Title: Journal of Medicinal Plants
Journal Index: Scopus
Volume: 3
Number: 11
ISSN: 16840240 (ISSN)
Depositing User: مهندس مهدی شریفی

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