Abstract

Introduction: Many people are used medicinal plants due to natural, low risks and complications, and low costs as compared with the synthetic drugs. Incidence of drug resistance against chemical antimicrobial drugs has led the use of medicinal plants for treatment of infections in recent years. The aim of this study was to examine possible antibacterial effects of four herbal plants in vitro. Materials and Methods: Four species of domestic plants from Fars- Fasa (Iran) including Ziziphora, Stachys, Teucrium and Barberry were collected in spring and dried. Hydro-alcoholic extracts of these plants were prepared using standard methods. Antibacterial effects were examined with disk diffusion method and serial broth dilution. To standardize of of study, we used antibiogram disks and ATCC bacteria. Results: Teucrium extract with 1/8 dilution and Barberry extract with 1/4 dilution showed antibacterial effects in serial dilution method. Moreover, by using the disk diffusion method, antibacterial effects of both mentioned extracts against E.coli ATCC 25922 and S.aureus ATCC 25923,were found as compared amoxicillin, ciprofloxacin, vancomycin and imipenem. Conclusion: The results of this study and other studies show that extracts of herbal plants, instead of chemical drugs, can be used to treat infections. Of course, before using them all their side effects should be carefully checked in in vitro and in vivo studies.