Abstract

Introduction: Approximately 40 of every adult human body mass is composed of skeletal muscle. Skeletal muscle diseases range from the debilitating to crippling and even to death. The residing satellite stem cells are few in numbers. The ability to take a few cells from an adult human and produce a large mass of functional skeletal muscle would be of invaluable benefit to humankind. Conclusion: As of today it seems that designing and construction of a skeletal muscle substitute with similar functional properties is a little far out of mind; because no yet exists an effective and executable method for construction of a skeletal muscle substitute that be large enough and mature and live fibers aligned in it with proper concentration and regularity similar to natural muscle.