(2011) Comparison of ondansetron and metoclopramide antiemetic prophylaxis in maxillofacial surgery patients. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology. pp. 275-277. ISSN 10792104 (ISSN)
Full text not available from this repository.
Abstract
Purpose: The purpose of this study was to compare the efficacy of ondansetron and metoclopramide, administered for the prophylaxis of vomiting in patients undergoing oral and maxillofacial surgery under general anesthesia. Methods: One hundred patients undergoing mandibular osteotomy surgery were studied. Patients were allocated randomly to receive 1 of 2 treatment regimens: 0.15 mg/kg ondansetron or 0.5 mg/kg metoclopramide intravenously 30 minutes before extubation. All were adults and were treated by one surgeon and all operations were the same and lasted 2.5 to 3.0 hours. The patients were assessed at 3 time periods: 0 to 3 hours, 3 to 12 hours, and 12 to 24 hours postoperatively for emesis. Result: The data from this study showed that during the first 24-hour postoperative period, patients receiving ondansetron following general anesthesia had an 11 (11 patients) incidence of emesis compared with 28 (22 patients) in the group that received metoclopramide. Conclusion: In this study, ondansetron (0.1 mg/kg) was twice as effective in preventing postoperative vomiting compared with metoclopramide. © 2011 Mosby, Inc.
| Item Type: | Article |
|---|---|
| Keywords: | antiemetic agent metoclopramide ondansetron adult article artificial ventilation clinical trial comparative study controlled clinical trial controlled study endotracheal intubation follow up human inhalation anesthesia intravenous drug administration mandible osteotomy postoperative nausea and vomiting premedication randomized controlled trial time treatment outcome Anesthesia, Inhalation Antiemetics Follow-Up Studies Humans Injections, Intravenous Intubation, Intratracheal Respiration, Artificial Time Factors |
| Divisions: | |
| Page Range: | pp. 275-277 |
| Journal or Publication Title: | Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology |
| Journal Index: | Scopus |
| Volume: | 111 |
| Number: | 3 |
| Identification Number: | https://doi.org/10.1016/j.tripleo.2010.04.034 |
| ISSN: | 10792104 (ISSN) |
| Depositing User: | مهندس مهدی شریفی |
| URI: | http://eprints.bmsu.ac.ir/id/eprint/1307 |
Actions (login required)
 |
View Item |