Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Detection and antimicrobial resistance properties of Staphylococcus aureus strains isolated from the human clinical infections

(2015) Detection and antimicrobial resistance properties of Staphylococcus aureus strains isolated from the human clinical infections. Biomedical and Pharmacology Journal. pp. 171-177. ISSN 09746242 (ISSN)

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Abstract

The present investigation was carried out to study the prevalence of Staphylococcus aureus and its antimicrobial resistance pattern isolated from various types of human clinical infections. One hundred and fifty clinical specimens were collected from the educational hospitals of Iran. Samples were cultured and those that were S. aureus-positive were confirmed using the PCR. Antimicrobial resistance pattern was analyzed using the disk diffusion method. Of 150 samples studied, 50 samples (33.33) were positive for S. aureus. The results of the culture method were confirmed using the PCR amplification of 16S rRNA gene of the S. aureus. Burn infections had the highest prevalence of S. aureus (40). S. aureus strains of our study harbored the highest levels of resistance against penicillin (94), tetracycline (92), oxacillin (90) and azithromycin (80). Keep the skin and especially wound and burn infections clean away from the polluted environment of hospitals and regular prescription of imipenem, methicillin and vancomycin may be good instructions to reduce the risk of S. aureus infections in the cases of human clinical infections.

Item Type: Article
Keywords: Antibiotic resistance properties Clinical infections Detection Iran Staphylococcus aureus amikacin ampicillin azithromycin chloramphenicol clindamycin cotrimoxazole erythromycin genomic DNA gentamicin imipenem meticillin norfloxacin oxacillin penicillin derivative RNA 16S tetracycline vancomycin antibiotic resistance antibiotic sensitivity Article bacterial growth bacterium colony bacterium culture bacterium identification burn infection controlled study disk diffusion Escherichia coli human inhibition zone nonhuman polymerase chain reaction postoperative infection prevalence risk reduction Staphylococcus infection wound infection
Divisions:
Page Range: pp. 171-177
Journal or Publication Title: Biomedical and Pharmacology Journal
Journal Index: Scopus
Volume: 8
Number: 1
Identification Number: https://doi.org/10.13005/bpj/596
ISSN: 09746242 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/396

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